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Nano coronavirus recombinant vaccine taking graphene oxide as carrier

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Current Assignee Shanghai National Engineering Research Center for Nanotechnology Co Ltd


Application CN202011031367.1A events: 

2020-09-27Application filed by Shanghai National Engineering Research Center for Nanotechnology Co Ltd

2020-09-27Priority to CN202011031367.1A

2021-01-15Publication of CN112220919A

Status: Pending

COMMENTO: la richiesta di brevetto risale al 27 settembre 2020 e risulta ancora in attesa di approvazione. Come si può leggere nella descrizione del brevetto, questo riguarda «un nuovo metodo di sviluppo di vaccini anti-coronavirus basato sull’ossido di grafene che funge da struttura per caricare molecole CpG e proteine ricombinanti» ed è stato al momento sperimentato sulle sole cavie da laboratorio. 

Abstract

The invention belongs to the field of nano materials and biomedicine, and relates to a vaccine, in particular to development of 2019-nCoV coronavirus nuclear recombinant nano vaccine. The invention also comprises a preparation method of the vaccine and application of the vaccine in animal experiments. The new corona vaccine contains graphene oxide, carnosine, CpG and new corona virus RBD; binding carnosine, CpG and neocoronavirus RBD on the backbone of graphene oxide; the CpG coding sequence is shown as SEQ ID NO 1; the novel coronavirus RBD refers to a novel coronavirus protein receptor binding region which can generate a high-titer specific antibody aiming at the RBD in a mouse body, and provides a strong support for prevention and treatment of the novel coronavirus.